Studies and Trials

The Birdshot Uveitis Society of North America provides information on ongoing clinical trials to support our mission of improving the understanding and treatment of birdshot uveitis. However, participation in any clinical trial involves certain risks and benefits that must be carefully considered. Please review the following important information before deciding to participate in a clinical trial:
  1. Informational Purposes Only: The information provided on our website regarding clinical trials is for informational purposes only. It should not be construed as medical advice or a recommendation for any specific treatment or participation in any specific clinical trial.
  2. Consult Your Healthcare Provider: Always consult with your healthcare provider before participating in any clinical trial. Your healthcare provider can help you understand the potential risks and benefits and determine whether a specific clinical trial is appropriate for your individual medical condition.
  3. No Endorsement: The Birdshot Uveitis Society of North America does not endorse or recommend any specific clinical trials, investigators, or institutions conducting these trials. Listing a clinical trial on our website does not imply endorsement by our organization.
  4. Voluntary Participation: Participation in clinical trials is entirely voluntary. You have the right to withdraw from a clinical trial at any time.
  5. Risks and Benefits: Clinical trials may involve risks, including potential side effects or adverse reactions. It is important to thoroughly discuss these risks with the trial investigators and your healthcare provider before participating. The potential benefits of participation are also variable and may not result in direct health improvements for participants.
  6. Confidentiality and Privacy: Clinical trials are conducted in accordance with strict ethical and legal standards to protect participants' confidentiality and privacy. Ensure you understand the measures in place to protect your personal information before enrolling in a trial.
  7. Updates and Changes: Clinical trial information may change over time. We strive to keep our information current, but we recommend checking directly with the trial sponsor or investigator for the most up-to-date information.
By accessing and using the clinical trial information on our website, you acknowledge that you have read and understood this disclaimer. The Birdshot Uveitis Society of North America is not liable for any decision you make regarding participation in clinical trials or any conseque>nces thereof.

CLARITY Study

Living with non-infectious uveitis (NIU)? The CLARITY Study could be for you! 

The CLARITY Study is testing an investigational oral medication called brepocitinib.  Brepocitinib is an investigational medication designed to block a part of the immune system involved in causing the inflammation associated with NIU. 

Eligibility: 

1.      Age 18 – 75 

2.      Have a diagnosis of non-infectious uveitis (intermediate, posterior or panuveitis) 

Participants may be reimbursed for time and travel. You are invited to chat with our study team and learn more.  

Discover if you may qualify at clarityuveitis.com

Birdshot Biobank

Do you have birdshot chorioretinopathy? Are you interested in participating in research to further understanding of this disease? Dr. Lucia Sobrin at the Mass. Eye and Ear Infirmary is leading a study to identify genetic markers, beyond HLA-A29, that increase the risk of birdshot chorioretinopathy.

The study involves a one-time blood draw and signing a form to allow the notes and eye images from your eye doctor’s office to be shared with Dr. Sobrin. 

If you are interested in participating, please contact the Center for Clinical Research Operations of

Mass. Eye and Ear at 617-573-6060 or Centerforclinicalresearchoperations@meei.harvard.edu .

Harvard medical school, Massachusetts eye and ear, and Massachusetts general hospital logos

MEERKAT and  SANDCAT trials

MEERKAT and  SANDCAT are clinical  trials recruiting patients with Uveitic Macular Edema.
The studies are currently enrolling patients across various
investigating sites in the United States, Canada and Internationally.
More information can be found on the Meerkat website and the Sandcat website